Contains specialized fungal enzymes from Aspergillus oryzae and Aspergillus melleus that mimic nattokinase activity.
Provides 2,500 fibrin units (FU) per capsule to support healthy blood flow and circulation.
Features traditional heart-supporting herbs including hawthorn berries and capsicum fruit.
Includes resveratrol, a powerful antioxidant compound that supports vascular health.
Offers a stable, soy-free alternative to nattokinase with convenient twice-daily dosing.

About Nature’s Sunshine Nattozimes Plus

Your cardiovascular system works around the clock to deliver oxygen and nutrients throughout your body. When blood flow becomes compromised by factors like poor circulation or excessive fibrin buildup, your heart has to work harder to maintain optimal function. Nature’s Sunshine Nattozimes Plus provides a scientifically formulated solution that supports healthy blood flow and cardiovascular wellness through the power of specialized enzymes and traditional botanicals.

This innovative formula serves as an effective alternative to nattokinase, a beneficial enzyme traditionally derived from fermented soybeans. While nattokinase has gained recognition for its cardiovascular benefits, it can be expensive, unstable, and problematic for those with soy sensitivities. Nattozimes Plus addresses these concerns by providing fungal-derived enzymes that deliver the same fibrinolytic activity without soy-related issues.

The Science Behind Enzyme Support

At the heart of this formula are specialized protease enzymes derived from Aspergillus oryzae and Aspergillus melleus fungi. These carefully selected enzyme strains have been shown to possess fibrinolytic activity, meaning they can help break down fibrin—a protein involved in blood clot formation. When fibrin levels become excessive, it can impact circulation and place additional stress on your cardiovascular system.

Each capsule delivers 2,500 fibrin units (FU), providing substantial enzymatic activity to support your body’s natural ability to maintain healthy blood flow. Unlike synthetic alternatives, these fungal enzymes work gently with your body’s existing systems to promote optimal circulation without unwanted side effects.

Traditional Botanicals for Heart Health

Beyond enzymes, Nattozimes Plus incorporates time-honored herbs that have been traditionally used to support cardiovascular wellness. Hawthorn berries bring their well-documented heart-supporting properties to this formula. These small, nutrient-rich fruits have been valued for centuries for their ability to support heart muscle function and overall cardiac health.

Capsicum fruit adds its circulation-promoting benefits, helping to support healthy blood flow throughout your body. This warming herb has a long history of use in traditional wellness practices for supporting cardiovascular function and maintaining healthy circulation patterns.

Dandelion leaf contributes additional support for cardiovascular health while providing gentle detoxification benefits. This common herb is rich in potassium and other minerals that support heart function and fluid balance throughout the body.

Resveratrol for Vascular Support

The formula is enhanced with resveratrol, a powerful antioxidant compound found in grape skins and other plants. This remarkable nutrient has gained significant attention for its potential cardiovascular benefits and ability to support healthy vascular function. Resveratrol helps protect blood vessels from oxidative stress while supporting the body’s natural inflammatory response.

Key Ingredients

Ingredient	Source	Traditional Use
Enzyme Blend	Aspergillus oryzae & melleus	Fibrinolytic activity, circulation support
Hawthorn Berries	Crataegus laevigata	Heart muscle support, cardiac function
Dandelion Leaf	Taraxacum officinale	Cardiovascular support, mineral content
Capsicum Fruit	Capsicum annuum	Circulation enhancement, warming properties
Resveratrol	Polygonum cuspidatum	Vascular support, antioxidant properties

Recommended Usage

Take 1 capsule between meals twice daily on an empty stomach. For best results, maintain consistent use and follow a heart-healthy lifestyle.

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per 1 Capsule	Amount	% Daily Value
Proprietary Blend Enzyme blend from Aspergillus oryzae and Aspergillus melleus, Hawthorn Berries (Crataegus laevigata, C. monogyna), Dandelion Leaf (Taraxacum officinale), Capsicum Fruit (Capsicum annuum), Resveratrol (from Polygonum cuspidatum root)	472 mg †	**
† Daily Value not established.
Other Ingredients: Capsule (gelatin, water), vegetable magnesium stearate, silicon dioxide.

Frequently Asked Questions

How does Nattozimes Plus compare to nattokinase?

Nattozimes Plus provides the same fibrinolytic activity as nattokinase but with greater stability and no soy content. The fungal enzymes in this formula mimic nattokinase’s action, delivering 2,500 fibrin units per capsule while being more cost-effective and suitable for those with soy sensitivities.

What are fibrin units and why are they important?

Fibrin units (FU) measure the enzyme’s ability to break down fibrin, a protein involved in blood clot formation. Each capsule provides 2,500 FU, which supports your body’s natural ability to maintain healthy blood flow and circulation by helping to manage fibrin levels.

When should I take this supplement for best results?

For optimal absorption and effectiveness, take Nattozimes Plus on an empty stomach between meals, twice daily. This timing allows the enzymes to work systemically without interference from food proteins that might compete for enzyme activity.

Are there any precautions I should be aware of?

Consult your healthcare provider before use if you’re taking blood-thinning medications or have a bleeding disorder. Do not use if you’re allergic to Aspergillus fungi. Always discontinue use if you experience any adverse reactions and consult with a healthcare professional.

How long should I take this supplement to notice benefits?

Individual results may vary, but many people find that consistent daily use for several weeks provides the best support for their cardiovascular wellness goals. This supplement works best as part of a comprehensive approach to heart health that includes proper diet and regular exercise.

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Who is Nattozimes Plus For?

Adults seeking natural cardiovascular support through enzyme therapy
Individuals interested in supporting healthy blood flow and circulation
People looking for a soy-free alternative to nattokinase supplements
Those wanting to combine traditional botanicals with modern enzyme science
Anyone interested in maintaining healthy fibrin levels as part of wellness routine